Will a 4 speed chevy sm465 tranny bolt up to a F engine?

not quite. You need an adapter for the bellhosing, clutch parts, and a transfercase adapter if you want to keep the cruiser t/c.

http://eshop.advanceadapters.com/commerce/catalog/product.jsp?product_id=1617

http://www.advanceadapters.com/tlc.html

http://www.root45.com/SM465Orion/

pretty simple, need to have the retainer machined down to fit the bellhousing and use hex head cap screws. Also need to run the spacer for the throwout and need a special throwout bearing.